Reference projects of Fraunhofer IESE

Successful projects from industry and research

In more than 2,000 customer projects, the institute has transferred cutting-edge research into sustainable business practices and innovative products.

Fraunhofer IESE supports you holistically in software, systems and innovation engineering. This covers the entire spectrum from strategic decisions in management to technical issues in the areas of architecture, implementation or testing.

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  • Digital Platform for Pharma 4.0: / 2026

    Virtual planning and certifiable quality in pharmaceutical manufacturing

    Industry: Digital Health / June 16, 2026

    Automated production technologies for mRNA -based drugs, Fraunhofer IESE
    © Ekaterina_1525/Alernon77/stock.adobe/Fraunhofer IZI

    As part of the VIMOPROP project, the Fraunhofer Institute for Experimental Software Engineering IESE developed a modular software platform designed to support pharmaceutical manufacturers in the virtual planning, simulation, and commissioning of production processes. The goal was to make the manufacture of complex and highly customized Advanced Therapy Medicinal Products (ATMPs), such as gene and cell therapies, more flexible, efficient, and compliant with regulatory requirements. In doing so, the strict requirements of pharmaceutical production are taken into account from the very beginning.

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  • AI and sustainability for small and medium-sized enterprises

    Induxtry: Smart City & Smart Region / February 13, 2026

    Mittelstand-Digital Zentrum Franken unterstützt kleine und mittlere Unternehmen (KMU) in Nordbayern, Fraunhofer IESE
    © Celine Schneider

    As part of the "Mittelstand-Digital" funding priority of the Federal Ministry for Economic Affairs and Energy, Fraunhofer IESE, together with Ansbach University of Applied Sciences, Nuremberg Tech, and the Academy for Artificial Intelligence (AKI), supports companies in classifying and introducing AI and sustainability in their own operations.

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  • Daten im Umlauf
    © iStock.com/monsitj

    UncertAInty (Uncertainty Quantification in AI Systems for International Compliance) is a WIPANO project funded by the Federal Ministry for Economic Affairs and Climate Action (BMWK) that advances the systematic handling of uncertainty in AI systems. Over a 30-month period, partners from industry, research, and standardization are working together to clearly describe uncertainties in AI, make them measurable, and standardize them internationally as part of the development of ISO/IEC TS 25223.

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  • Success Story: DIHK, Fraunhofer IESE
    © Fraunhofer IESE

    Fraunhofer IESE has collaborated with the DIHK to design a digital ecosystem for register modernization in order to realize opportunities through platform business models for commercial registers. To this end, IESE has tailored and applied its proven and flexible methods for modeling ecosystems to the context of register modernization in a specific application.

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  • Success Story OnViewMed
    © iStock.com/Tippapatt

    The aim of the “OneViewMed” (OVM) project was to significantly improve the information situation for medical staff. Work processes were to be simplified and patient safety further increased. To achieve this, Fraunhofer IESE developed a graphical dashboard together with medical staff and the IT departments of Frankfurt University Hospital in order to facilitate the work of medical staff and ensure interoperability between the IT systems used on different wards.

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  • Innovative security solutions

    Industry: Automotive & Mobility, Commercial Vehicles / March 20, 2025

    Innovative Sicherheitsösungen
    © AdobeStock.com/rejekimoyex; Fraunhofer IESE

    How Fraunhofer IESE and Robert Bosch GmbH make complex safety-critical applications automatically testable using Linux as the operating system platform.

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  • LLM supported automatic structuring of medical data

    Industry: Artificial intelligence / January 23, 2025

    Webinar LLM Teil 2 Retrieval Augmented Generation RAG
    © iStock.com | Greyfebruary

    In the public project FHIR-Starter, Fraunhofer IESE and its project partners are researching ways of automatically analyzing full-text medical documents, such as findings, using large language models and making them available as FHIR resources in an interoperable manner - here we place particular emphasis on safeguarding and avoiding hallucinations.

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  • “Digital twin Hattersheim” concept

    Branche: Smart City / December 17, 2024

    smart city, urbaner digitaler zwilling, stadt, virtuell

    The “Digital Twin Hattersheim” project is developing a concept that forms the basis for the implementation of an Urban Digital Twin for the future-oriented planning of Hattersheim's city center.

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  • Digital Health
    © iStock.com/ipopba

    Apoplex Medical Technologies, based in Pirmasens, Germany, is a specialized service provider for cloud-based applications that support clinics and medical practices in the early detection of stroke risks. With automated ECG data analysis, Apoplex enables medical professionals to identify risks at an early stage and take targeted preventive measures. The solutions are flexible and available at any time, making preventive work easier in everyday clinical practice.

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